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Convergence of the EBT method for a non-local model of cell proliferation with discontinuous interaction kernel

Autor
Szymańska, Zuzanna
Gwiazda, Piotr
Miasojedow, Błażej
Skrzeczkowski, Jakub
Data publikacji
2022
Abstrakt (EN)

We consider the EBT algorithm (a particle method) for the nonlocal equation with a discontinuous interaction kernel. The main difficulty lies in the low regularity of the kernel, which is not Lipschitz continuous, thus preventing the application of standard arguments. Therefore, we use the radial symmetry of the problem instead and transform it using spherical coordinates. The resulting equation has a Lipschitz kernel with only one singularity at zero. We introduce a new weighted flat norm and prove that the particle method converges in this norm. We also comment on the two-dimensional case that requires the application of the theory of measure spaces on general metric spaces and present numerical simulations confirming the theoretical results. In a companion paper we apply the Bayesian method to fit parameters to this model and study its theoretical properties.

Słowa kluczowe EN
particle method
EBT algorithm
measure solutions
flat metric
nonlocal equation
convergence analysis
cancer modelling
Dyscyplina PBN
matematyka
Czasopismo
IMA Journal of Numerical Analysis
ISSN
0272-4979
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