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Synthesis of novel chiral guanidine catalyst and its application in the asymmetric Pictet-Spengler reaction

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dc.abstract.enA new chiral guanidine catalyst has been synthesized by the reaction of (R)-1-(1-phenylethyl)guanidine and 2,3-diphenylcycloprop-2-enone. The catalyst was evaluated for the Pictet-Spengler reaction in which tetrahydro-β-carbolines were obtained in good yields with up to 64% ee.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorAhmad, Saeed
dc.contributor.authorShukla, Lakshmi
dc.contributor.authorCzarnocki, Zbigniew
dc.contributor.authorMaurin, Jan
dc.contributor.authorSzawkało, Joanna
dc.contributor.authorRoszkowski, Piotr
dc.date.accessioned2024-01-26T09:26:53Z
dc.date.available2024-01-26T09:26:53Z
dc.date.issued2017
dc.description.financeNie dotyczy
dc.description.volume89
dc.identifier.doi10.1016/J.CATCOM.2016.10.008
dc.identifier.issn1566-7367
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/121312
dc.identifier.weblinkhttps://www.sciencedirect.com/science/article/pii/S1566736716303739
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofCatalysis Communications
dc.relation.pages44-47
dc.rightsClosedAccess
dc.sciencecloudnosend
dc.subject.enCyclopropenone
dc.subject.enChiral guanidine catalyst
dc.subject.enOrganocatalysis
dc.subject.enPictet-Spengler reaction
dc.subject.enTryptamines
dc.titleSynthesis of novel chiral guanidine catalyst and its application in the asymmetric Pictet-Spengler reaction
dc.typeJournalArticle
dspace.entity.typePublication