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Porphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine

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dc.abstract.enPorphyrin ligands, showing a significant affinity for cancer cells, also have the ability to chelate metallic radioisotopes to form potential diagnostic radiopharmaceuticals. They can be applied in single-photon emission computed tomography (SPECT) and positron emission tomography (PET) to evaluate metabolic changes in the human body for tumor diagnostics. The aim of this paper is to present a short overview of the main metallic radionuclides complexed by porphyrin ligands and used in these techniques. These chelation reactions are discussed in terms of the complexation conditions and kinetics and the complex stability.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorPęgier, Mateusz
dc.contributor.authorKilian, Krzysztof
dc.contributor.authorPyrzyńska, Krystyna
dc.date.accessioned2024-01-25T17:16:18Z
dc.date.available2024-01-25T17:16:18Z
dc.date.copyright2022-05-21
dc.date.issued2022
dc.description.accesstimeBEFORE_PUBLICATION
dc.description.financePublikacja bezkosztowa
dc.description.number10
dc.description.versionFINAL_PUBLISHED
dc.description.volume27
dc.identifier.doi10.3390/MOLECULES27103311
dc.identifier.issn1420-3049
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/116553
dc.identifier.weblinkhttps://www.mdpi.com/1420-3049/27/10/3311/pdf
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofMolecules
dc.relation.pages3311
dc.rightsCC-BY
dc.sciencecloudnosend
dc.subject.enporphyrins
dc.subject.enmetallic radionuclides
dc.subject.ensingle-photon emission computed tomography
dc.subject.enpositron emission tomography
dc.titlePorphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine
dc.typeJournalArticle
dspace.entity.typePublication