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Super-resolution enhancement by quantum image scanning microscopy

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dc.abstract.enThe principles of quantum optics have yielded a plethora of ideas to surpass the classical limitations of sensitivity and resolu-tion in optical microscopy. While some ideas have been applied in proof-of-principle experiments, imaging a biological sample has remained challenging, mainly due to the inherently weak signal measured and the fragility of quantum states of light. In principle, however, these quantum protocols can add new information without sacrificing the classical information and can therefore enhance the capabilities of existing super-resolution techniques. Image scanning microscopy, a recent addition to the family of super-resolution methods, generates a robust resolution enhancement without reducing the signal level. Here, we introduce quantum image scanning microscopy: combining image scanning microscopy with the measurement of quantum pho-ton correlation allows increasing the resolution of image scanning microscopy up to twofold, four times beyond the diffraction limit. We introduce the Q-ISM principle and obtain super-resolved optical images of a biological sample stained with fluores-cent quantum dots using photon antibunching, a quantum effect, as a resolution-enhancing contrast mechanism.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorBatel, R.
dc.contributor.authorRossman, U.
dc.contributor.authorOron, D.
dc.contributor.authorŁapkiewicz, Radosław
dc.contributor.authorSilberberg, Y.
dc.contributor.authorZonatan, I.
dc.contributor.authorTenne, R.
dc.contributor.authorKrupinski+Ptaszek, A.
dc.date.accessioned2024-01-26T09:24:26Z
dc.date.available2024-01-26T09:24:26Z
dc.date.issued2019
dc.description.financeNie dotyczy
dc.description.volume13
dc.identifier.doi10.1038/S41566-018-0324-Z
dc.identifier.issn1749-4885
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/121140
dc.identifier.weblinkhttps://www.nature.com/articles/s41566-018-0324-z.pdf
dc.languageeng
dc.pbn.affiliationphysical sciences
dc.relation.ispartofNature Photonics
dc.relation.pages116–122
dc.rightsClosedAccess
dc.sciencecloudnosend
dc.titleSuper-resolution enhancement by quantum image scanning microscopy
dc.typeJournalArticle
dspace.entity.typePublication