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Synthesis and Characterization of Magnetic Drug Carriers Modified with Tb3+ Ions

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cris.lastimport.scopus2024-02-12T20:55:29Z
dc.abstract.enThe study aimed to synthesize and characterize the magnetic drug carrier modified with terbium (III) ions. The addition of terbium extends the possibilities of their applications for targeted anticancer radiotherapy as well as for imaging techniques using radioisotopes emitting β+, β−, α, and γ radiation. The synthesis of iron oxide nanoparticles stabilized with citrates using the co-precipitation method (IONP @ CA) was carried out during the experimental work. The obtained nanoparticles were used to synthesize a conjugate containing terbium ions and guanosine-5′-monophosphate as an analog of drugs from the thiopurine group. Conjugates and their components were characterized using Transmission Electron Microscopy, infrared spectroscopy, X-ray microanalysis, spectrofluorimetry, and thermogravimetric analysis. The hybrid was also investigated with Langmuir layers to check the interaction with analogs of biological membranes
dc.affiliationUniwersytet Warszawski
dc.contributor.authorKrysiński, Paweł
dc.contributor.authorŻuk, Michał
dc.contributor.authorKońska, Paulina
dc.contributor.authorCichy, Dariusz
dc.contributor.authorRękorajska, Aleksandra
dc.contributor.authorNieciecka, Dorota
dc.date.accessioned2024-01-26T09:26:19Z
dc.date.available2024-01-26T09:26:19Z
dc.date.copyright2022-02-26
dc.date.issued2022
dc.description.accesstimeAT_PUBLICATION
dc.description.financePublikacja bezkosztowa
dc.description.number5
dc.description.versionFINAL_PUBLISHED
dc.description.volume12
dc.identifier.doi10.3390/NANO12050795
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/121276
dc.identifier.weblinkhttps://www.mdpi.com/2079-4991/12/5/795/pdf
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofNanomaterials
dc.relation.pages795
dc.rightsCC-BY
dc.sciencecloudnosend
dc.subject.enmagnetic nanoparticles
dc.subject.endrug carriers
dc.subject.enmagnetic hyperthermia
dc.subject.enLangmuir monolayers
dc.titleSynthesis and Characterization of Magnetic Drug Carriers Modified with Tb3+ Ions
dc.typeJournalArticle
dspace.entity.typePublication