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Cover Feature: Fluorescent Turn‐On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap‐Recognizing Proteins (Chem. Eur. J. 27/2019)

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cris.lastimport.scopus2024-02-12T19:44:10Z
dc.abstract.en7‐Methylguanine nucleotides labelled with pyrene were found to behave as sensitive turn‐on probes upon enzymatic cleavage or binding to specific proteins. This observation served as the basis for developing binding‐ and hydrolytic‐activity assays in a 96‐well format for two therapeutically‐relevant 7‐methylguanosine cap recognising proteins: translation initiation factor (eIF4E) and decapping enzyme (DcpS). A complex of eIF4E with pyrene labelled nucleotide is depicted on the cover. More information can be found in the Full Paper by J. Kowalska, J. Jemielity, et al. on page 6728.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorKasprzyk, Renata
dc.contributor.authorKubacka, Dorota
dc.contributor.authorKowalska, Joanna
dc.contributor.authorCiechanowicz, Sylwia
dc.contributor.authorStarek, Beata J.
dc.contributor.authorJemielity, Jacek
dc.date.accessioned2024-01-24T20:54:09Z
dc.date.available2024-01-24T20:54:09Z
dc.date.issued2019
dc.description.financeNie dotyczy
dc.description.number27
dc.description.volume25
dc.identifier.doi10.1002/CHEM.201901431
dc.identifier.issn0947-6539
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/103851
dc.identifier.weblinkhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201901431
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofChemistry - A European Journal
dc.relation.pages6646-6646
dc.rightsClosedAccess
dc.sciencecloudnosend
dc.titleCover Feature: Fluorescent Turn‐On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap‐Recognizing Proteins (Chem. Eur. J. 27/2019)
dc.typeJournalArticle
dspace.entity.typePublication