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How Surface-Enhanced Raman Spectroscopy Could Contribute to Medical Diagnoses

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dc.abstract.enIn the last decade, there has been a rapid increase in the number of surface-enhanced Raman scattering (SERS) spectroscopy applications in medical research. In this article we review some recent, and in our opinion, most interesting and promising applications of SERS spectroscopy in medical diagnostics, including those that permit multiplexing within the range important for clinical samples. We focus on the SERS-based detection of markers of various diseases (or those whose presence significantly increases the chance of developing a given disease), and on drug monitoring. We present selected examples of the SERS detection of particular fragments of DNA or RNA, or of bacteria, viruses, and disease-related proteins. We also describe a very promising and elegant ‘lab-on-chip’ approach used to carry out practical SERS measurements via a pad whose action is similar to that of a pregnancy test. The fundamental theoretical background of SERS spectroscopy, which should allow a better understanding of the operation of the sensors described, is also briefly outlined. We hope that this review article will be useful for researchers planning to enter this fascinating field.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorSzaniawska, Aleksandra
dc.contributor.authorMazur, Kinga
dc.contributor.authorKwarta, Dominika
dc.contributor.authorPyrak, Edyta
dc.contributor.authorKudelski, Andrzej
dc.date.accessioned2024-01-25T03:30:22Z
dc.date.available2024-01-25T03:30:22Z
dc.date.copyright2022-05-19
dc.date.issued2022
dc.description.accesstimeBEFORE_PUBLICATION
dc.description.financePublikacja bezkosztowa
dc.description.number5
dc.description.versionFINAL_PUBLISHED
dc.description.volume10
dc.identifier.doi10.3390/CHEMOSENSORS10050190
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/108691
dc.identifier.weblinkhttps://www.mdpi.com/2227-9040/10/5/190/pdf
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofChemosensors
dc.relation.pages190
dc.rightsCC-BY
dc.sciencecloudnosend
dc.subject.enSERS
dc.subject.ensurface-enhanced Raman spectroscopy
dc.subject.ennanosensor
dc.subject.enbiosensor
dc.subject.enmedical
dc.subject.encells
dc.subject.enDNA
dc.subject.enmultiplexing
dc.titleHow Surface-Enhanced Raman Spectroscopy Could Contribute to Medical Diagnoses
dc.typeJournalArticle
dspace.entity.typePublication