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Enzymatic syntheses of 3’-halotyramines, selectively 2H- and 3H-labeled in the side chain

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dc.abstract.en3’-Halotyramines, stereo-selectively labeled with deuterium and tritium, in the (1R) or (1S) position were synthesized using enzymatic methods. The isotopomers labeled in the (1R) position were synthesized by enzymatic decarboxylation of an appropriate 3’-halo-L-tyrosine in deuterated or tritiated incubation medium. The isotopomers labeled in the (1S) position were synthesized by decarboxylation of an appropriate 3’-halo-L-tyrosine, labeled with deuterium or tritium in the α-position of the side chain.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorPająk, Małgorzata
dc.contributor.authorKańska, Marianna
dc.date.accessioned2024-01-24T22:49:28Z
dc.date.available2024-01-24T22:49:28Z
dc.date.issued2018
dc.description.financeNie dotyczy
dc.description.volume131
dc.identifier.doi10.1016/J.APRADISO.2017.10.032
dc.identifier.issn0969-8043
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/106310
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofApplied Radiation and Isotopes
dc.relation.pages8-12
dc.rightsClosedAccess
dc.sciencecloudnosend
dc.subject.enDeuterium
dc.subject.enEnzyme
dc.subject.enLabeling
dc.subject.enTritium
dc.subject.enTyramine
dc.titleEnzymatic syntheses of 3’-halotyramines, selectively 2H- and 3H-labeled in the side chain
dc.typeJournalArticle
dspace.entity.typePublication