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Mechanosynthesis of Eutectics of Anti‐Inflammatory Drug Ethenzamide – A Comparison with Analogous Cocrystals

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cris.lastimport.scopus2024-02-12T19:38:16Z
dc.abstract.enMechanochemical milling of ethenzamide (ETZ), a nonsteroidal anti-inflammatory drug, with substituted aromatic carboxylic acids as well as anti-tuberculosis drug pyrazinamide (PZA) resulted in the formation of eutectics. Although a large number of cocrystals as well as polymorphic cocrystals are reported for ETZ, for the first time we have synthesized six eutectics including an instance of a drug-drug eutectic system. Supramolecular synthon energy calculations validate the for- mation of eutectic mixtures over cocrystals with coformers considered in our study.
dc.affiliationUniwersytet Warszawski
dc.contributor.authorRajbongshi, Trishna
dc.contributor.authorSarmah, Kashyap Kumar
dc.contributor.authorThakuria, Ranjit
dc.contributor.authorGanduri, Ramesh
dc.contributor.authorCherukuvada, Suryanarayan
dc.contributor.authorArhangelskis, Mihails
dc.date.accessioned2024-01-25T11:26:33Z
dc.date.available2024-01-25T11:26:33Z
dc.date.copyright2021-06-22
dc.date.issued2021
dc.description.accesstimeAT_PUBLICATION
dc.description.financePublikacja bezkosztowa
dc.description.number9
dc.description.versionFINAL_PUBLISHED
dc.description.volume1
dc.identifier.doi10.1002/CMTD.202100016
dc.identifier.issn2628-9725
dc.identifier.urihttps://repozytorium.uw.edu.pl//handle/item/112231
dc.identifier.weblinkhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/cmtd.202100016
dc.languageeng
dc.pbn.affiliationchemical sciences
dc.relation.ispartofChemistry—Methods
dc.relation.pages408-414
dc.rightsOther
dc.sciencecloudnosend
dc.subject.encomputational chemistry · mechanochemistry · eutectic systems · cocrystal · supramolecular synthon
dc.titleMechanosynthesis of Eutectics of Anti‐Inflammatory Drug Ethenzamide – A Comparison with Analogous Cocrystals
dc.typeJournalArticle
dspace.entity.typePublication