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Dostęp zamkniętySynthesis and Characterization of Tb-Doped Nanoferrites
| cris.lastimport.scopus | 2024-02-12T19:37:38Z |
| dc.abstract.en | Tb3+-substituted superparamagnetic iron-oxide-based nanoparticles (NPs) that can be promising for possible multimodal drug carrier and radiotherapy are presented. These NPs were obtained using a reverse micelle template method with controlled micelle size. The atomic ratio of Tb/Fe ions was found to be very close to that expected from the stoichiometry of the reagents used. Aqueous suspensions of Tb-doped nanoferrites are emissive with emission peaks characteristic for the Tb3+ dopant. Time-resolved fluorescence decay data revealed two populations occupying inequivalent matrix sites. Above 80 K the Tb-doped nanoferrites were superparamagnetic, which is a prerequisite for their use as carriers in magnetic-field-driven targeted therapies. The incorporation of up to 15 at.% of Tb3+ in their core resulted in a decrease of magnetization. Nevertheless, this magnetization appears to be sufficient for their use as carriers in an external magnetic field, and, of equal importance, stable isotope 159Tb3+ could be replaced by radioactive 161Tb3+, yielding multimodal NPs, suitable for conjugated therapies such as radiotherapy and magnetothermal therapy, as well as targeted drug delivery. |
| dc.affiliation | Uniwersytet Warszawski |
| dc.contributor.author | Cichowicz, Grzegorz |
| dc.contributor.author | Grdeń, Michał |
| dc.contributor.author | Cyrański, Michał |
| dc.contributor.author | Blanchard, Gary |
| dc.contributor.author | Rękorajska, Aleksandra |
| dc.contributor.author | Krysiński, Paweł |
| dc.contributor.author | Pękała, Marek |
| dc.date.accessioned | 2024-01-26T09:26:21Z |
| dc.date.available | 2024-01-26T09:26:21Z |
| dc.date.issued | 2018 |
| dc.description.finance | Nie dotyczy |
| dc.description.number | 2 |
| dc.description.volume | 4 |
| dc.identifier.doi | 10.1002/CNMA.201700344 |
| dc.identifier.uri | https://repozytorium.uw.edu.pl//handle/item/121279 |
| dc.language | eng |
| dc.pbn.affiliation | chemical sciences |
| dc.relation.ispartof | ChemNanoMat |
| dc.relation.pages | 231-242 |
| dc.rights | ClosedAccess |
| dc.sciencecloud | nosend |
| dc.subject.en | magnetic properties |
| dc.subject.en | magnetothermal therapy |
| dc.subject.en | nanoparticles |
| dc.subject.en | radiotherapy |
| dc.subject.en | terbium |
| dc.title | Synthesis and Characterization of Tb-Doped Nanoferrites |
| dc.type | JournalArticle |
| dspace.entity.type | Publication |